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Research Project Project ID: R6561

Title To examine the use of IgA for quantifying the influence of nutrition on the immune response of small ruminants to gastrointestinal nematode parasites.
Species Goat, Sheep
Commodity Non-specific
Livestock Keeper Group Smallstock Keepers
Production System Non-specific
Country or Region Tanzania
Research Theme Health
Research Approach Laboratory based
Funding Agency DFID Animal Health Research Programme

 

 

Summary

  • Gastrointestinal parasites such as Haemonchus contortus are an enormous constraint on the efficient production of sheep in developing countries where such stock are mainly owned by poorer farmers.
  • Haemonchus contortus induces protein deficiency, which has the effect of weakening the host response and promoting parasite survival.


 
Primary Relevance Low - High
Feeding and Nutrition
Animal Health
Commodities and Markets  
Other Husbandry
Policy Relevance

Documents

Understanding the Interaction between Level of Nutrition and Gastrointestinal parasites

Helping lambs to control stomach worms before they get sick

  • This DFID project successfully evaluated the use of the antibody Immunoglobulin A (IgA) as a way of quantifying the influence of nutrition on the immune response of small ruminants to gastrointestinal parasites.
  • IgA appears to suppress worm growth and fecundity and thus acts as a major mechanism of resistance to these worm infections
  • Animals on low protein diets are more susceptible to infection because they produce less IgA. Farmers can counter this by feeding extra protein.
  • Measuring the amount of parasite-specific IgA can indicate which animals are nutritionally stressed or identify those animals that are relatively resistant to infection. A cheap test is now required so that this information can be incorporated into livestock management strategies.

The majority of sheep in
developing countries are
infested with gastrointestinal
parasites such as
Haemonchus contortus
.

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