Regular use of anthelmintics results in the development of
anthelmintic resistant nematodes. This is likely to be aggravated in
regions of high rainfall where year round treatment is required. In
times of extended drought, where the only worms that reproduce in
the new wet season are those that have survived treatment in the
host, resistance is also likely to be worse. Kenya thus has two
climatic conditions likely to encourage the selection for
anthelmintic resistant nematodes. Existing publications and
conversations with veterinary surgeons suggest that resistance is
already quite widespread.
Two major factors enhancing for the selection and spread of
anthelmintic resistant nematodes are underdosing and movement
of animals (Coles and Roush, 1992). Poor farmers trying to
economise on anthelmintics and are breeding improved stock for
sale to peasant farmers provide an excellent method of distribution
of resistance in addition to normal movement of animals. The
relatively high reliance on group 2 anthelmintics (levamisole/
morantel) suggests that few people are practising rotation of
anthelmintic types, a management system that is believed to slow
the development of resistance.
Kenya thus has the potential for large problems with anthelmintic
resistant nematodes on both ranches and in peasant farming.
Obviously the availability of simple, inexpensive but reliable tests
for anthelmintic resistant nematodes would be very valuable in
determining the extent of the problem. Such tests need validating
may be the incentive to apply strategies that should limit the
development and spread of resistant nematodes.
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