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Research Project Project ID: R4901

Title Helminth zoonoses
Species Pigs
Commodity Meat
Livestock Keeper Group Smallstock Keepers, Landless Livestock keepers
Production System Non-specific
Country or Region Swaziland, Nepal, Kenya, Niger, Nigeria & Mexico
Research Theme Health
Research Approach Laboratory based
Funding Agency DFID Animal Health Research Programme

 

 

Summary

A sero-epidemiology study for T. saginata cysticercosis, conducted using the antigen - ELISA developed at CTVM, on samples taken from cattle attending dip tanks in Swaziland , has given an indication of the prevalence and incidence of this parasite in the country.

Several recombinant clones which were isolated from a cDNA library prepared from T. saginata oncospheres and which may be of protective significance have been grown up and are currently in store awaiting further analysis prior to proposed vaccine trials.

 
Primary Relevance Low - High
Feeding and Nutrition  
Animal Health
Commodities and Markets  
Other Husbandry
Policy Relevance

Documents

Project Summary

Hybridoma cell lines thought to be producing monoclonal antibodies reactive with bovine IgE are being recloned and immunochemical evaluation has been carried out on the monoclonal antibodies.

Studies into the comparative pathogenicity of Fasciola gigantica fasciolosis in Eastern Nepal have indicated that buffaloes are surprisingly susceptible to infection.

Immunity stimulated by drug treatment of early gastrointestinal nematode infections in a mouse has been shown to influence the resistance of the animals to concurrent trypanosome infections. These findings support the suggestion that further studies should be conducted in sheep.

Immunochemical analysis of excretions and secretions of Fasciola hepatica at various ages as it develops in the definitive host has resulted in the identification of candidate protective/diagnostic antigens.

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